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Stefano Donadio: Scientific and economic challenges in the discovery and development of new antibiotics Scientific and economic challenges in the discovery and development of new antibiotics

Seminar: Mikrobiologi

23.10.2019 | Anne Kirstine Mehlsen

Dato tir 29 okt
Tid 14:15 15:00
Sted Building 1593, room 012, iNANO Auditorium, Interdisciplinary Nanoscience Center, Aarhus University

Foredragsholder: PhD Stefano Donadio, CEO and founder of Naicons

ABSTRACT:

The increasing and widespread emergence of multi-drug resistant bacterial pathogens calls for multiple strategies to tackle this serious threat, including the development of new antibiotics not affected by existing resistance mechanisms. Despite heavy investments, no effective technology is available to discover promising antibacterial scaffolds, with natural products, especially those of microbial origin, still representing a major source of approved drugs and of new scaffolds. However, discovery of new antibiotics from nature remains challenging. Furthermore, the current economic and regulatory scenario does not encourage the development of new treatments for bacterial infections and most major pharmaceutical companies are no longer involved in this field. In the course of the presentation, I will provide a brief overview on NAICONS’ history, its technology platform, its business model and the approaches to discovery new bioactive molecules. I will also report some recent examples on new chemical classes of bioactive molecules and how they were discovered.

Everybody is welcome – coffee & cake will be served.

Thomas Tørring (Department of Engineering - Microbial Biosynthesis)
Andreas Schramm (Department of Bioscience – Microbiology)

Want to meet the speaker: contact thomast@eng.au.dk

Next seminars:
12 November 2019:
Professor Nadine Ziemert, University of Tübingen, Germany.
10 December 2019:
Professor Lone Gram & Associate Professor Mikael Lenz Strube, Technical University of Denmark

Institut for Bioscience, Offentligheden / Pressen, Medarbejdere, Mikrobiologi